Evaluation of diuretic activity of root extract of Mangifera indica in albino rats

Background: Diuretics increase urine flow and sodium excretion are used to maintain the volume composition of body fluids in a variety clinical situations Objectives: To evaluate diuretic activity alcoholic (AERMI) extract roots Mangifera indica albino rats. Methods: 5 groups Albino rats were by using metabolic cages. The group I serves as normal control received vehicle, II Furosemide (10 mg/Kg, p.o) ; other III, IV, V treated with low, medium, high doses AERMI immediately after treatment all hydrated saline (15 ml/kg) placed Total collected was measured at end h. Concentration Sodium, Potassium, Chloride estimated. Results: Compared different dose levels (100,200 400 mg/kg) has significantly increased also enhanced elimination Potassium Chloride. Conclusion: Single 100, 200 mg/Kg Frusemide have output along an concentration